Austin Chapter of the American Statistical Association
The urine protein-creatinine ratio (UPC) is used as an index of magnitude of proteinuria that is widely used to assess renal disease. This study was performed to determine the number of serial UPC measurements needed to reliably estimate the actual UPC level. Since the variance of the UPC increases at higher levels of UPC, we model the variance as a function of the mean using maximum likelihood estimation.
This is joint work with Mary Nabity, George Lees (College of Vet. Medicine TAMU) and Clifford Kashtan (University of Minisota Medical School).