TL43: Covariate Adjustment: Should study center be included?
*Caiyan Li, Baxter Healthcare
In we write SAP for clinical trials, we often are required to specify a primary analysis (model) to identify the covariates in the model. It is important to build a model with the important covariates included. It is controversial how to evaluate the study center effect and whether it should be included in the model: as fixed effects (with or without interaction term), random effects. This roundtable intends to have a discussion on this topic based on participants' practical experiences. Three questions to discuss: 1. In what situations should we include study center as a covariate in the model? What's the advantages and disadvantages? 2. How should study center be integrated, as fixed or random effects? 3. What's your experience when evaluating study center effect?
April 30 - May 22, 2013
Invited Abstract Submission Open
June 4, 2013
Online Registration Opens
August 9 - August 23, 2013
Invited Abstract Editing
August 23, 2013
Short Course materials due from Instructors
August 26, 2013
September 9, 2013
Cancellation Deadline and Registration Closes @ 11:59 pm EDT
September 16 - September 18, 2013
Marriott Wardman Park, Washington, DC