RL09 Statistical Challenges in Alzheimer's Disease (AD) Clinical Trials
*Yonggang Zhao, Wyeth 


This round table will discuss the various statistical challenges in AD clinical trials for symptomatic and disease modifying claims. Topics to be discussed include, but are not limited to, study design, co-primary endpoints, statistical models to demonstrate symptomatic improvement and disease modifying effect, regulatory challenges in global AD trials, and claims from key secondary endpoints and biomarkers.