TL51: Margin selection in non-inferiority trials
*Chul Ahn, FDA 


Non-inferiority trials are not simply underpowered superiority trials. In general, non-inferiority trials are more challenging to design, conduct and interpret. In this roundtable, we will discuss and share the experience on some of the practical issues with non-inferiority trials, especially, the selection of non-inferiority margin.